"If I ate an Inuit diet, extremely low in plants and high in fats from oily fish and blubbery mammals, my blood vessels would soon be screaming out for mercy. The Inuit themselves have no such problem. They have long since adapted to their distinctive diet, and have several unusually common variants in genes that metabolize fatty acids."
These are the first sentences of an interesting article reviewing genetic variation among small groups in climatic extremes and what the"rest" of us humans can learn from this. The article has links to some of the original research. If you are interested in the topic, or in the possibilities of human adaptation to extreme conditions, to changing conditions, it is worth while.